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Change from baseline of heart rate and blood pressure immediately after infusion of S-methyl-l-thiocitrulline (SMTC; 1.0 µmol/kg) and SMTC (3.0 µmol/kg) and saline vehicle placebo over 10 min. A, Heart rate (ΔHR); (B) diastolic blood pressure (ΔDBP); (C) mean arterial pressure (ΔMAP); and (D) systolic blood pressure (ΔSBP). *P<0.05 compared with placebo; **P<0.01 compared with placebo.
