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Change from baseline of (A) stroke volume (SV), (B) cardiac output (CO), (C) mean arterial blood pressure (MAP), and (D) systemic vascular resistance (SVR) immediately after infusion of S-methyl-l-thiocitrulline (SMTC; 3.0 µmol/kg) and saline vehicle placebo over 10 min. *P<0.05 compared with placebo; **P<0.01 compared with placebo.
