Figure 3.

Extended funnel plot demonstrating the effect size and se combinations required of an additional randomized study to change the results of this meta-analysis using a fixed effects model with an alpha level of 0.05. Black dots represent the effect size and ses of the included randomized studies. To change the results of the meta-analysis to favor antipyretics, an additional study would need to have an effect estimate and se combination that falls in the dark grey shaded area. Note that none of the current studies have an effect size-se in the dark grey region; this suggests that the results of the meta-analysis would be robust to an additional study.