Figure 2.
White matter tracts associated with age and learning. (A–D) White matter tracts in a representative subject between the VTA-NAcc (A), NAcc-DMThal (B), DMThal-MPFC (C), and MPFC-NAcc (D) and corresponding scatter plots across participants. The thalamocortical (C) and corticostriatal (D) tracts were associated with both age (N = 25) and learning (N = 22). (E) A combined measure of thalamocorticostriatal (TCS) white matter integrity mediated age differences in reward learning. Reprinted from [37].