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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Exp Gerontol. 2017 Feb 9;90:83–89. doi: 10.1016/j.exger.2017.01.025

Table 3.

Significant CSF/SNP correlations. All significant results after Bonferroni adjustment were with the GRN SNP (rs5848_T). The parameter estimates (beta and std. err.) reflect the log-transformations of CSF analytes and can be exponentiated for a fold-change interpretation after adjustment for gender, diagnosis, years of education, age at lumbar puncture and the first 3 principal components. AXL = AXL Receptor Tyrosine Kinase; TRAIL-R3 = TNF-Related Apoptosis-Inducing Ligand Receptor 3; VCAM-1 = Vascular Cell Adhesion Molecule-1; CLU = clusterin.

CSF Analyte beta est. std. err. Nominal p-value Bonferroni-corrected p-value
AXL 0.704 0.149 3.95E-06 0.001
TRAIL-R3 0.064 0.015 2.11E-05 0.007
VCAM-1 0.052 0.013 4.96E-05 0.016
CLU 0.062 0.016 9.19E-05 0.031