Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 28;45(5):e34. doi: 10.1093/nar/gkw1086

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — The individual steps that make up the sCNAphase workflow. (A) Each panels shows an individual process used by sCNAphase to characterize the copy number profile from matched tumor and normal pairs. (B) The B-allele frequencies (BAFs) from a region of chromosome 8 from the HCC1143 breast cancer cell-line. (C) The application of phasing to the BAF data makes it possible to identify parental-haplotype frequencies (PHFs), regions composed of 40 adjacent germline, heterozygous single nucleotide polymorphisms (SNPs). Each PHF increase the power of this analysis and makes it possible to better reflect the copy number profile of this region. (D) Application of the sCNAphase pipeline to the phased data, calls specific copy number changes.