Table 3. The capacity of sCNAphase to detect the focal sCNAs in COSMIC.
HCC1143 15 focal amplification from COSMIC | HCC1954 94 focal amplification from COSMIC | HCC1187 2 focal amplification from COSMIC | HCC2218 18 focal amplification from COSMIC | |||||
---|---|---|---|---|---|---|---|---|
Tumor purity | Sen | Spe | Sen | Spe | Sen | Spe | Sen | Spe |
100% | 80 | 23 | 66 | 52 | 100 | 26 | 61 | 31 |
80% | 80 | 24 | 67 | 47 | 100 | 25 | 56 | 31 |
60% | 80 | 24 | 63 | 47 | 100 | 27 | 44 | 38 |
40% | 67 | 28 | 61 | 52 | 100 | 30 | 78 | 25 |
20% | 80 | 22 | 65 | 57 | 100 | 30 | 61 | 44 |
10% | 87 | 29 | 77 | 52 | 100 | 23 | 61 | 48 |
5% | 80 | 23 | 37 | 93 | 100 | 29 | 22 | 100 |
Sen for sensitivity; Spe for specificity.