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Mechanisms of action underlying the function of RNA G4s. RNA G4 binding to RBP (A), RBP binding to both DNA and RNA G4 (B), intermolecular G4 formed by DNA and RNA strands (C), equilibrium between RNA G4 and hairpin conformation (D), RNA G-rich sequence that can fold into a G4 or hybridize with the C-rich template DNA strand in the R-loop structure (E).
