FIG. 5.

Inhibition of LT-mediated elongation by antisera generated in animals immunized with SC608 or its derivatives. The images show CHO cells treated with PBS (A), LT (25 ng/ml) (B), LT mixed with pooled sera from guinea pigs immunized with normal saline (NS) (C), LT plus SC608(p3098) (D), LT plus SC608(pCFAI) (E), and LT plus SC608(pCFAI/LTB) (F). (G) Antisera were serially diluted in PBS and mixed with a constant amount (25 ng/ml) of LT. The percent inhibition was calculated by taking elongation with 25 ng of LT/ml alone as 0% inhibition and the extent of elongation without LT as 100% inhibition.