Table 4. Breakdown of indels divisible by two and three nucleotides by genomic context.

	Multiple of three bp		Multiple of two bp
	% Observed indels (count)	P-value (expected ratio = one third)	% Observed indels (count)	P-value (expected ratio = one half)
Exon	86.7% (13/15)	3.14 × 10−5	53.3% (8/15)	1
Non-exon	6.71% (10/149)	9.61 × 10−15	87.2% (130/149)	<2.2 × 10−16

% (and raw count) of observed indels from the 3D7 clone tree which were divisible by two and three nucleotides are shown, broken down into those occurring inside and outside of exons (outside of exons includes both introns and non-genic loci). By chance, the expected proportions of indels divisible by three and two base pairs are one third and one half, respectively. P-values are derived from binomial exact tests. Indels that were multiples of three bp were more likely to occur in exons, while introns and non-genic loci were more likely to contain indels that were multiples of 2 bp. Data also shown in Figure 4.