FIG. 2.

Inhibition of antibody binding to AMA1 constructs with homologous and heterologous allelic forms. Binding to AMA1 antigens coated onto the ELISA plates (3D7, D10, or HB3 sequence as indicated) was inhibited with soluble antigen 3D7 AMA1 (squares), D10 AMA1 (triangles), or HB3 AMA1 (circles). The AMA1 constructs (coated and inhibitor) were the full ectodomain or domain III as indicated. A) Plasma sample VGS30, full ectodomain; B) plasma sample VGS54, full ectodomain; C) plasma sample VGS88, full ectodomain; D) plasma sample VGS34, domain III.