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IOP–Time profiles obtained with THC-Val-HS and THC in rabbit glaucoma model. Numbers in brackets represent concentration (%w/v) and dose equivalent to THC (μg). Actual baseline values (mean ± SEM in mm Hg) for IOP in the different formulations: THC-Val-HS in Tocrisolve (26.8 ± 0.4), THC-Val-HS in micellar solution (26.8 ± 0.2), and THC (0.8% w/v) in Tocrisolve (24.5 ± 1.9).
