. 2017 Apr 12;12(4):e0175479. doi: 10.1371/journal.pone.0175479

Table 1. Association between SNPs in the SLCO1B1 gene and CYP4 cluster and hexadecanedioate levels in the meta analysis carried out by Shin et al (2014)[7], in the extremes of BP carried out by Padmanabhan et al (2010)[11], in the ICBP consortium GWAS(2011)[10] and with risk of statin associated myopathy as reported (SEARCH collaborative group 2008)[14].

Gene	SNP	EA	hexadecanedioate-TUK KORA meta-analysis Nat Gen			HTN extreme GWAS			ICBP			Risk of statin associated myopathy
Gene	SNP	EA	BETA	SE	P	BETA	SE	P	BETA	SE	P	BETA	SE	P
SLCO1B1	rs4149056	T	-0.088	0.006	1.65x10^-51	-0.006	0.031	0.86	-0.12	0.13	0.34^*	-1.51	0.258	4.0x10^-9
	rs2900478	A	0.087	0.006	2.02x10^-50	0.022	0.029	0.50
	rs7969341	A	-0.086	0.006	2.67x10^-49	-0.022	0.029	0.50
	rs4363657	T	-0.085	0.006	3.92x10^-48	-0.022	0.029	0.49				-1.51	0.258	4.0x10^-9
	rs4149081	A	0.084	0.006	9.67x10^-48	0.021	0.029	0.50
	rs11045879	T	-0.084	0.006	1.56x10^-47	-0.022	0.029	0.49
	rs2199680	A	-0.084	0.006	4.52x10^-47	-0.018	0.029	0.57
	rs12366582	A	-0.083	0.006	2.28x10^-46	-0.019	0.029	0.55
	rs12369881	A	0.083	0.006	2.28x10^-46	0.019	0.029	0.54
	rs12371604	T	-0.069	0.005	2.85x10^-42	-0.002	0.026	0.96
	rs4149054	A	0.054	0.005	6.26x10^-26	0.027	0.027	0.37
	rs4149050	T	-0.052	0.005	1.23x10^-24	-0.027	0.027	0.37
	rs4149058	A	-0.052	0.005	2.06x10^-24	-0.026	0.027	0.37
	rs4149057	T	0.039	0.004	2.00x10^-19	0.023	0.023	0.36
	rs11045656	A	0.026	0.004	5.39x10^-9	0.064	0.025	0.02
CYP4	rs6663731	A	0.045	0.007	5.49x10^-11	0.067	0.035	0.08	-0.041	0.147	0.92
	rs9332998	T	0.04	0.007	4.19x10^-9	0.068	0.036	0.08	-0.002	0.148	0.99

* Beta(SE), P Value for SNP rs12317268 that is in complete LD (R2 = 1) with rs4149056