Table 3:
Anatomic Location | Hemisphere | MNI Coordinates of Global Maxima |
||
---|---|---|---|---|
X | Y | Z | ||
Fractional anisotropy, control > ABI | ||||
PLIC | L | −22 | −12 | 7 |
PLIC | R | 20 | −8 | 8 |
Corpus callosum, splenium | R | 20 | −38 | 31 |
Mean diffusivity, ABI > control | ||||
Superior corona radiata | R | 27 | −8 | 44 |
Superior corona radiata | L | −21 | −24 | 43 |
Internal capsule | R | 25 | 2 | 20 |
Internal capsule | L | −26 | −2 | 22 |
External capsule | R | 29 | −6 | 18 |
External capsule | L | −32 | −11 | 9 |
Note:—MNI indicates Montreal Neurological Institute; L, left; R, right.
Location and coordinates of peaks of significant white matter abnormalities in FA and MD are reported (P < .001; clusters, >100 mm3). White matter tissue labels derived from the Johns Hopkins University ICBM-DTI-81 atlas.