A 71-year-old man with acute onset weakness of the left upper extremity presented with an area of acute infarction (blue arrow) along the deep posterior cortex of the right precentral gyrus involving the hand motor region, with A, relative hypointensity on MPRAGE, B, hyperintensity on FLAIR, and C, restricted diffusion on the ADC map. The patient also has an area of chronic infarction more anteriorly (red arrow), showing A, relative hypointensity on MPRAGE, B, hyperintensity on FLAIR, and C, T2 shine through on the ADC map. ROIs in the affected areas (D) show higher and lower CT, respectively, compared with contralateral analogous brain (E); however, mGM as a marker of cortical volume was higher in the acute infarct, as expected, but also higher in the chronic infarct.