Table 1.
Iron status measurements at birth from comparison neonates categorized as iron replete (n =19) vs iron-deficient infants (n =6) at birth
| Patient group | Biochemical measures of iron deficiency
|
Measures of iron-deficient erythropoiesis
|
Measures of iron deficiency anemia
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Ferritin (ng ml −1) | Iron (μg dl −1) | Sat (%) | Soluble transferrin receptor (mg l −1) | ZPP to heme ratio | Retic hemoglobin content (pg) | MCV (fl) | Hgb (g dl −1) | Hct (%) | |
| SGA, n = 1 | 11 | 79 | 26 | 9.8 | 202 | 29.6 | 108.2 | 16.3 | 48.6 |
| IDM, n = 1 | 35 | 71 | 29 | 6.9 | 75 | 30.5 | 100.9 | 15.4 | 45.7 |
| VLBW, n = 1 | 21 | 75 | 25 | 10.8 | 199 | 36.1 | 114.3 | 17.6 | 51.8 |
| VLBW, n = 1 | 22 | 51 | 24 | 10.2 | 127 | 32.8 | 118.2 | 18.0 | 53.9 |
| VLBW, n = 1 | 42 | 38 | 19 | 5.3 | 114 | 38.6 | 103.7 | 14.8 | 42.1 |
| Preterm (31 w), n = 1 | 24 | 28 | 13 | 10.8 | 130 | 36.0 | 116.2 | 17.9 | 53.0 |
| Interquartile range comparison group n = 19 | 81–200 | 130–190 | 61–100 | 3.6–5.0 | 70–95 | 33.2–37.5 | 101.9–109.7 | 14.7–16.7 | 41.4–47.7 |
Abbreviations: Hct, hematocrit; Hgb, blood hemoglobin concentration; IDM; infant of diabetic (type I or type II) mother; MCV, mean corpuscular volume; Sat, saturation of iron binding with iron; SGA, small-for-gestational-age ( < 10th percentile weight for gestational age at birth); VLBW, very-low-birth weight ( < 1500 g); ZPP, zinc protoporphyrin. Individual values are shown for the six judged as having biochemical iron deficiency. Median and interquartile ranges are shown for the comparison neonates.