TABLE 2.
S. flexneri genes showing more than a 3-fold difference in intracellular expression level between HeLa and U937 cells
| Gene name
|
Gene expression levels in the following cells at the indicated time (h), relative to those in LB medium:
|
Function or comments | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Common | Systematic | HeLa
|
U937
|
||||||
| 2 | 4 | 6 | 8 | 1 | 3 | 5 | |||
| asr | SF1618 | 1.9 | 2.3 | 3.6 | 3.7 | 20.3 | 17.5 | 17.8 | Acid shock protein |
| bioB | SF0724 | 7.1 | 4.1 | 3.7 | 3.5 | 0.6 | 0.8 | 0.7 | Biotin synthesis |
| bioF | SF0726 | 4.9 | 2.9 | 2.4 | 2.4 | 0.5 | 0.6 | 0.6 | KAPA synthetaseb |
| emrKa | SF2435 | 1.6 | 2.1 | 3 | 3.4 | 23.6 | 38.5 | 36.1 | Multidrug resistance protein K |
| emrYa | SF2434 | 2.5 | 3.9 | 5.5 | 5.4 | 13 | 24.7 | 21.5 | Multidrug resistance protein Y |
| gadAa | SF3594 | 2.4 | 6.8 | 4.4 | 3.3 | 68.3 | 25.2 | 10.9 | Glutamate decarboxylase isozyme |
| gadBa | SF1734 | 2.5 | 7.4 | 4.6 | 3.5 | 71.3 | 25.6 | 11.2 | Glutamate decarboxylase isozyme |
| hdeAa | SF3544 | 0.5 | 0.9 | 0.5 | 0.3 | 6 | 2.4 | 1.2 | Conserved hypothetical protein |
| nrdI | SF2702 | 10.1 | 15.5 | 18.8 | 18.3 | 3.3 | 4.1 | 5.9 | Conserved hypothetical protein |
| SF2147 | SF2147 | 0.9 | 1 | 0.9 | 1 | 11.6 | 11.5 | 10.7 | Function unknown |
| SF2148 | SF2148 | 2 | 2 | 2.5 | 2.5 | 48.1 | 42.5 | 38.6 | Conserved hypothetical protein |
| ydeOa | SF1537 | 1.4 | 1.8 | 3.2 | 3.5 | 30 | 25 | 24.9 | AraC-type regulatory protein |
| ydePa | SF1538 | 2.9 | 4.4 | 5.1 | 5.2 | 130.8 | 93.9 | 70.5 | Acid resistance protein |
| yedX | SF2017 | 1.5 | 1.9 | 2.9 | 2.9 | 11.6 | 15.3 | 12.2 | Conserved hypothetical protein |
| yfdUa | SF2440 | 4 | 4.8 | 7 | 7.1 | 216.4 | 113 | 62.5 | Function unknown |
| yfdVa | SF2439 | 2.3 | 2.7 | 4.1 | 4.7 | 75.1 | 38.6 | 21.6 | Putative receptor protein |
| yfdWa | SF2441 | 5.1 | 5.6 | 8.1 | 8.2 | 266.1 | 173.7 | 101.4 | Function unknown |
| yhiEa | SF3546 | 1 | 1.3 | 1.7 | 1.6 | 20.2 | 11.8 | 5.9 | Acid resistance protein |
a
Member of the EvgA or YdeO regulon.
b
KAPA, 7-keto-8-amino-perlargonic acid.