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. 2017 Apr 13;8:139. doi: 10.3389/fneur.2017.00139

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Copyright © 2017 Tanner, McFarland and Price.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Parkinson’s disease (PD) and non-PD subcortical shape only differences. Note: areas in red indicate where groups are significantly different (FDR-corrected p < 0.05). Areas in red indicate significant F-values, which in this case are all areas of atrophy (inward vertex displacement) in PD relative to non-PD peers. Relative to non-PD, L-PD have more right than left putamen and caudate nucleus atrophy and R-PD have more left than right caudate nucleus atrophy but more right than left putamen atrophy (see Table 3). (A) All PD (n = 72) versus non-PD (n = 48); (B) left onset PD (n = 27) versus non-PD (n = 48); (C) right onset PD (n = 45) versus non-PD (n = 48).