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. 2017 Apr 6;133(5):665–704. doi: 10.1007/s00401-017-1707-9

Fig. 4.

Fig. 4

Tau localisation in neurons. Schematic depicts the differing locations of neuronal tau, the majority of which is associated with the microtubule cytoskeleton in axons. Tau is also located in the somatodendritic compartment, including in mitochondria, the nucleus, plasma membrane, and synapses. Dendritic tau (indicated in red) is increased in the tauopathies