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. 2017 Apr 11;112(7):1328–1338. doi: 10.1016/j.bpj.2017.02.031

Figure 2.

Figure 2

Calorimetric isotherms obtained by titrating Trp into TRAP at different experimental temperatures reveal multimode, cooperative binding, with different Kd, ΔH, and ΔCp, although at lower temperatures those features cannot be discerned.