Figure 1.

Schematic of the five force-generation mechanisms in mitotic spindles, including the pushing force generated by MT polymerization (inset 1), the pulling force general by cortical dynein (inset 2), the pushing force generated by cortical kinesin (inset 3), the pulling force generated by cytoplasmic dynein (inset 4), and the pushing force generated by kinesin on the antiparallel MTs. The chromosome provides similar forces to the cortex in insets 1–3 (dotted box). To see this figure in color, go online.