Figure 6.

Volume-sensing mechanism versus boundary-sensing mechanism. (a–c) Spindle length scaling in uncompressed and compressed extract droplets (in vitro). Spindle length in extract droplets is plotted as the function of (b) cell volume and (c) cell length. Astral MTs are removed here because they are lacking in the spindles assembled in the extract droplets. (d–f) Spindle length scaling in uncompressed and compressed cells (in vivo). The solid lines are obtained by solving the minimal analytical model. To see this figure in color, go online.