TABLE 3.

Published LD₅₀s for rabbits and nonhuman primates

Animal	B. anthracis challenge		LD50 (CFU)	95% confidence interval	Method	Reference
	Isolate	Route
Rabbit	Ames	Subcutaneous	1.6 × 103	NRa	Probit	88
Rabbit	Ames	Inhalation	1.1 × 105	NR	Probit	88
Rhesus macaque	Ames	Inhalation	5.5 × 104	NR	Probit	46
Rhesus macaque	Vollum	Inhalation	5.0 × 104	NR	Probit	27
Cynomolgus	Ames	Inhalation	6.2 × 104	(3.5-11.0) × 104	Probit	83
Cynomolgus	NR	Inhalation	4.1 × 103	(2.0-8.6) × 103	SKc	31
Chimpanzee	Vollum	Inhalation	3.7 × 105	NDb	NR	2

^aNR, not reported.

^bND, could not be calculated due to the small sample size.

^cSK, Spearman-Karber method.