Table 2.
Potential determinant factors for MDR-TB at St. Peter hospital in Addis Ababa, Ethiopia
| Clinical Characteristics | Options | MDR-TB N=103 | Non- MDR-TB N=103 | Bivariate Analysis COR, 95% CI | p-value |
|---|---|---|---|---|---|
| History of TB | Yes | 96 (93.2%) | 25 (24.3%) | 42.79 (17.57,104.17) | <0.001 |
| No | 7 (6.8%) | 78 (75.7%) | 1 | ||
| COPD | Yes | 17 (17.7%) | 21 (20.6%) | 0.83 (0.41,1.69) | 0.607 |
| No | 79 (82%) | 81 (79.4%) | 1 | ||
| HIV infected | Yes | 19 (18.4%) | 48 (46.6%) | 0.26 (0.14,0.49) | <0.001 |
| No | 84 (81.6%) | 55 (53.4%) | 1 | ||
| TB episodes | One | 34 (33.0%) | 90 (87.4%) | 1 | |
| Two or more | 69 (67.0%) | 13 (12.6%) | 14.05 (6.89, 28.63) | <0.001 | |
| Biological site of TB | Pulmonary | 92 (93.9%) | 21 (80.8%) | 3.65 (1.017,13.10) | 0.047 |
| Extra-pulmonary | 6 (6.1%) | 5 (19.2%) | 1 | ||
| Followed DOTs strategy | Yes | 83 (80.6%) | 92 (89.3%) | 1 | |
| No | 20 (19.4%) | 11 (10.7%) | 2.07 (0.486, 10.60) | 0.08 | |
| Treatment category | Category I | 48 (46.6%) | 96 (94.1%) | 1 | |
| Category II | 39 (37.9%) | 2 (2.0%) | 39.0 (9.03, 168.37) | 0.045 | |
| Category III | 5 (4.9%) | 3 (2.9%) | 3.33 (0.76, 14.54) | ||
| Category IV | 11 (10.7%) | 1 (1.0%) | 2.82 (1.27, 175.44) | ||
| Ever interrupted anti-TB drug therapy | Yes | 24 (23.3%) | 10 (9.7%) | 2.82 (1.27, 6.26) | 0.011 |
| No | 79 (76.7%) | 93 (90.3%) | 1 | ||
| History of travel outside the country | Yes | 88 (85.4% | 90 (87.4%) | 1.18 (0.53, 2.62) | 0.68 |
| No | 15 (14.6%) | 13 (12.6%) | 1 | ||
| History of contact with confirmed TB case | Yes | 36 (35.6%) | 31 (30.1%) | 1 | |
| No | 65 (64.4%) | 72 (69.9%) | 0.78 (0.43, 1.40) | 0.40 | |
| Smoked cigarettes | Yes | 16 (15.5%) | 20 (19.4%) | 0.76 (0.37, 1.57) | 0.46 |
| No | 87 (84.5%) | 83 (80.6%) | 1 | ||
| Consumed alcohol | Yes | 30 (29.1%) | 42 (40.8%) | 1.29 (0.71, 2.31) | 0.08 |
| No | 73 (70.9%) | 61 (59.2%) | 1 | ||
| Chat chewed | Yes | 24 (23.3%) | 18 (17.5%) | 1.43 (0.72, 2.84) | 0.301 |
| No | 79 (76.7%) | 85 (82.5%) | 1 |