Table 1.
Number of Genes Regulated Downstream of the Activated/Inhibited TFs from Phase I
| Number of TFs Act/Inh in Phase I | Regulated Genes in Osteogenic Phase I | Regulated Genes in Osteogenic Phase II | Regulated Genes in Osteogenic Phase III | |
|---|---|---|---|---|
| OS only | 4 | 112 | 260 | 438 |
| OS and AD | 10 | 151 | 272 | 441 |
| All OS | 14 | 192 | 408 | 693 |
| Osteoblast specific | 36.6% | 52.3% | 57.5% | |
| Number of TFs Act/Inh in Phase I | Regulated Genes in Adipogenic Phase I | Regulated Genes in Adipogenic Phase II | Regulated Genes in Adipogenic Phase III | |
| AD only | 20 | 170 | 492 | 647 |
| OS and AD | 10 | 181 | 431 | 533 |
| All AD | 30 | 235 | 706 | 964 |
| Adipocyte specific | 31.8% | 55.9% | 66.6% | |