FIG. 2.

Molecular characterization of the A. nidulans PpoC locus. The ppoC genomic DNA sequence contains 11 introns and 12 exons. The major transcription initiation site was found 136 bp upstream of the first ATG codon, and the polyadenylation site (polyA) is located 128 bp downstream from the ORF stop codon. The deduced translated 1,117-amino-acid polypeptide contains predicted heme peroxidase and cytochrome P-450 domains and a sequence that aligns with the proline knot motif, an essential motif for targeting proteins to lipid bodies. Arrows indicate the conserved proline residues.