Figure 4. Venn diagram of Propionibacterium freudenreichii candidate genes identified as potentially being associated with anti-inflammatory properties, using omics methods (genomics, transcriptomics and surface proteomics).

The numbers of candidates are those for which the regression model provides an adjusted p-value < 0.05 for the association. The regression model also provides a sign (+) or (−) corresponding to positive and negative associations with the induction of IL-10. (+) clusters are associated with IL-10 induction by anti-inflammatory strains whereas the reverse is true for (−) clusters. The names of the genes are specified for those mentioned in the text of the publication and in Table 1.