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. 2017 Apr 15;9(4):142–152. doi: 10.4251/wjgo.v9.i4.142

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Molecular classification of colorectal cancer. The figure shows the different molecular profile and clinic-histopathological characteristics of each classification. CIMP: CpG island methylator phenotype; MSI: Microsatellite instability; MS: Microsatellite stability; CRC: Colorectal cancer; CIN: Chromosomal instability; HNPCC: Hereditary nonpolyposis colorectal cancer; MGMT: O-6-methylguanine-DNAmethyltransferase; BRAF: v-raf murine sarcoma viral oncogene homologe B1; MLH1: MutL homolog 1; KRAS: Kirsten rat sarcoma 2 viral oncogene homolog; APC: Adenomatosis polyposis coli; TP53: Tumor protein p53.