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. 2017 Apr 13;18:295. doi: 10.1186/s12864-017-3675-9

Table 1.

Shared DE genes for Ross vs. Illinois between thermoneutral and heat stress conditions

Gene Symbol Thermoneutral Heat Stress Gene Function
P-value Log2FC FDR P-value Log2FC FDR
STMN1 5.30E-05 1.24 0.023 0.0003 −1.59 0.066 Regulates microtubule dynamics in cell division [105]
CDC45 5.11E-05 1.34 0.023 0.00046 −1.71 0.076 Key replication helicase cofactor in DNA replication [70]
DNA2 7.47E-06 1.71 0.0078 5.99E-05 −2.31 0.030 Essential DNA-helicase for chromosome replication [106]
CCNB2 0.00025 1.17 0.065 0.00042 −1.63 0.075 Important regulator required for cell mitosis [107]
dAK 0.00028 1.46 0.070 1.88E-08 −3.33 0.00011 Crucial regulator for DNA precursor synthesis [108]
MKLP1 6.14E-05 1.10 0.025 0.00046 −1.40 0.076 Mediates cell cycle cytokinesis [109]
CDC20 2.28E-06 1.58 0.0032 0.00029 −1.74 0.065 Regulates chromosome segregation and mitotic exit [110]
SMC2 0.00023 1.32 0.064 2.81E-06 −2.44 0.0042 Essential for chromosome segregation and condensation [111]
FXYD2 1.08E-08 −2.03 6.08E-05 3.36E-09 3.00 3.79E-05 Required for ion transport in heart [112]
SNTB1 7.48E-06 −1.09 0.0078 6.21E-05 1.41 0.030 Involved in muscle contraction [113]
KIAA1210 0.00017 −1.26 0.052 0.00011 1.87 0.046 Unknown
AVD 2.15E-06 −3.55 0.0032 2.05E-05 4.43 0.016 Unknown
AGTR1 0.00012 −3.51 0.041 2.95E-06 6.00 0.0042 Important role in pathogenesis of cardiac hypertrophy [85]
PERP 0.00012 −1.05 0.040 7.78E-06 1.78 0.0098 Mediates p53-dependent apoptosis [114]

Log 2 FC: log2 fold change, FDR: False Discovery Rate