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. 2017 Apr 13;14:9. doi: 10.1186/s12979-017-0091-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Transcript expression ratio’s in middle-aged compared to young LSC. The mRNA transcript expression in the LSC of 3 month and 17-month-old Fisher 344 male rats were assessed and 21,700 probe sets were measureable. The horizontal axis indicates the log₂ ratios of middle aged over young expression and the vertical axis is the –log₁₀ of the FDR corrected p values. ~ 1100 transcripts were differentially expressed. Blue dots represent genes that increased or decreased by at least 1.5 fold (528)