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. 2017 Apr 13;16:147. doi: 10.1186/s12936-017-1805-0

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Structures and activities of 10 selected anti-gametocyte compounds. Structures and concentration-response curves of selected lead compounds (NCGC00114940, NCGC00134134, NCGC00134128, NCGC00134154, NCGC00134126, NCGC00134132, NCGC00104490, NCGC00134130, NCGC00134124, and NCGC00106780) determined in the gametocyte viability assay (green), asexual parasite growth assay (blue) and HepG2 cytotoxicity assay (red). Cluster names are included. Data are presented as mean ± SD with n = 3 independent experiments