Plasma, femur, and liver Zn concentrations of male weanling rats fed high-fat diets differing in Zn content and fat source for 4 wk. Columns represent means ± SDs, n = 8. Labeled means without a common letter differ, P < 0.05 (1-factor ANOVA followed by Tukey's multiple-comparison test). Bifactorial ANOVA of the LZ-CB, HZ-CBR, LZ-SF, and HZ-SFR: significance (P) of Zn, fat, and zinc × fat is <0.001, <0.001, and 0.098 for plasma Zn, <0.001, 0.006, and 0.82 for femur Zn, and 0.13, 0.32, and 0.54 for liver Zn concentrations, respectively. Diet groups: LZ-CB, low-Zn (LZ) cocoa butter (CB) diet fed free choice; HZ-CBR, high-Zn (HZ) CB diet fed in restricted amounts equivalent to intake of the LZ-CB diet; LZ-SF, LZ safflower oil (SF) diet fed free choice; HZ-SFR, HZ-SF diet fed in restricted amounts equivalent to intake of the LZ-SF diet; HZ-SF, HZ-SF diet fed free choice.