Weight loss time course. In females, significant weight loss was observed in the DSS + RSV group compared with that in the CTRL from day 8 and in the DSS + RSV group when compared with that in the DSS group from day 10. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001, in comparison with the control; #p < 0.05 and ##p < 0.01, DSS + RSV in comparison with DSS. In males, there was no significant difference between the groups. Significant differences between sexes were observed in the CTRL groups on day 8 and in the DSS + RSV on day 10. ∗p < 0.05, males in comparison with females. CTRL, control; DSS, dextran sulfate sodium; RSV, resveratrol.