Table 3.

Pathways enriched by subnetwork modules.

Module	Gene set	Protein from module	FDR
0	Transcriptional regulation of white adipocyte differentiation (R)	6	2.72E − 05
0	Chromatin modifying enzymes (R)	6	2.03E − 03
1	Mitotic metaphase and anaphase (R)	23	2.00E − 15
1	Signaling by Rho GTPases (R)	21	2.00E − 15
3	Synthesis of DNA (R)	11	4.44E − 16
3	S phase (R)	11	4.44E − 16
4	DNA damage bypass (R)	8	9.99E − 16
4	Fanconi anemia pathway (N)	9	9.99E − 16
5	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway (P)	5	1.74E − 05
5	Wnt signaling pathway (P)	6	2.86E − 05
6	Protein kinase a at the centrosome (B)	2	6.92E − 03
6	Prostate cancer (K)	3	6.92E − 03
7	Signaling by Rho GTPases (R)	8	4.73E − 10
7	Regulation of RhoA activity (N)	2	1.07E − 02
8	Mitotic telophase/cytokinesis (R)	4	7.08E − 09
8	Mitotic prometaphase (R)	4	8.56E − 06
9	Interferon alpha/beta signaling (R)	5	6.83E − 09
9	ISG15 antiviral mechanism (R)	4	6.35E − 07
10	Cadherin signaling pathway (P)	6	4.47E − 09
10	Wnt signaling pathway (P)	6	7.94E − 07
11	Nucleosome assembly (R)	9	5.55E − 16
11	Mitotic prometaphase (R)	6	1.36E − 10
12	Beta1 integrin cell surface interactions (N)	4	4.71E − 08
12	ECM-receptor interaction (K)	3	2.45E − 05
13	Formation of fibrin clot (clotting cascade) (R)	2	1.36E − 02
13	AP-1 transcription factor network (N)	2	2.12E − 02
14	TGF-beta signaling pathway (P)	4	4.87E − 06
14	TGF-beta signaling pathway (K)	4	4.87E − 06
15	Insulin-mediated glucose transport (N)	2	9.27E − 03
15	Class I PI3K signaling events mediated by Akt (N)	2	9.27E − 03

The source of pathway database: C: CellMap, R: Reactome, K: KEGG, N: NCI PID, P: Panther, and B: BioCarta.