Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Evaluation of probe reactivity using a glutathione (GSH) model. (A) Structures of the HZyne and AOyne probes. (B) Scheme of the GSH model. After the thiol group of GSH reacts with HNE through Michael addition, the HZyne and AOyne probes are used to capture the remaining aldehyde group on the adduct. (C) The extracted ion chromatographic peaks of GSH, the HNE-GSH adduct, and the final products formed with the HZyne and AOyne probes, respectively.
