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. 2017 Apr 13;7:45487. doi: 10.1038/srep45487

Figure 3. BENAQ selectively photosensitizes RGCs from degenerated but not healthy retina.

Figure 3

(a,b) MEA recording from a WT mouse retina before (a) and after ex vivo (b) treatment with 300 μM BENAQ. (c) RGC PLRI values for WT retinas before (black) and after (green) treatment with BENAQ (n = 6 retinas, p = 0.34). (d,e) MEA recordings from BENAQ-treated pharmacologically isolated WT (d) and rd1 (e) RGCs. (f) LRI values for synaptically isolated untreated (black, n = 5 retinas) and BENAQ-treated (red, n = 5 retinas) WT RGCs, as well as for untreated (blue, n = 5 retinas), BENAQ-treated (green, n = 11 retinas) and BENAQ+ cilobradine treated (yellow, n = 4 retinas) rd1 RGCs. Data are mean ± SEM.