Table 2.

Brain regions showing increased negative connectivity with the medial orbitofrontal cortex (mOFC) when winning money and receiving pain simultaneously

			MNI peak coordinates in mm
Brain region	Cluster size (mm3)	z score peak	x	y	z
adACC	1824	2.78	8	38	20
SI (hand area)	1400	2.88	42	−30	58
rostral anterior insula	584	2.30	38	14	−10

Brain areas that showed increased negative connectivity with the mOFC in the PPI analysis when receiving monetary reward and pain at the same time (significant on a voxel-based threshold of z = 1.6 and cluster threshold of P < 0.05 within the regions of interest (RoIs) anterior insula, ACC, and postcentral gyrus (Worsley et al. 1996)). Local maxima within the clusters are given for individual anatomical areas. SI, primary somatosensory cortex; adACC, anterior-dorsal anterior cingulate cortex.