Table 5.
Significant activations in the contrasts of interest over all participants and between group differences
| Side | Cluster size (Voxel) | Peak voxel MNI coordinates (mm) |
Peak Z score | |||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Emotional vs neutral prosody | ||||||
| Cluster 1 | 15077 | |||||
| Lingual gyrus | R | 20 | −56 | −4 | 4.79 | |
| Planum temporale | L | −64 | −22 | 12 | 4.67 | |
| Superior temporal gyrus | L | −62 | −22 | 6 | 4.57 | |
| Planum temporale | L | −20 | −58 | −6 | 4.55 | |
| −64 | −26 | 16 | 4.43 | |||
| Angular gyrus | L | −38 | −48 | 20 | 4.44 | |
| Cluster 2 | 1523 | |||||
| Middle cingulate cortex | L/R | 10 | −2 | 40 | 4.33 | |
| −10 | −10 | 36 | 3.66 | |||
| Posterior cingulate cortex | L/R | −12 | −26 | 44 | 3.72 | |
| −12 | −30 | 44 | 3.7 | |||
| Supplementary motor cortex | L/R | −10 | 4 | 40 | 3.49 | |
| Superior frontal gyrus | L/R | −8 | −36 | 50 | 3.38 | |
| Complex > basic emotional prosody in controls > ASD | ||||||
| Cluster 1 | 3169 | |||||
| Planum temporale | R | 38 | −34 | 10 | 6.27 | |
| 42 | −30 | 10 | 6.14 | |||
| 52 | −18 | 6 | 4.25 | |||
| Parietal operculum cortex | 44 | −34 | 24 | 3.9 | ||
| Planum polare | R | 46 | 2 | −14 | 3.78 | |
| 44 | −12 | −4 | 3.56 | |||
| Superior temporal sulcus | R | 56 | −38 | 10 | 2.94 | |
| Amygdala | R | 26 | −4 | −22 | 2.74 | |
| Cluster 2 | 2284 | |||||
| Heschl’s gyrus | −44 | −22 | 2 | 4.39 | ||
| Superior temporal sulcus | L | −64 | −8 | −6 | 4.36 | |
| Superior temporal gyrus | L | −64 | −6 | 0 | 4.16 | |
| Planum temporale | L | −50 | −22 | 2 | 3.75 | |
| Central opercular cortex | L | −58 | −8 | 8 | 3.59 | |
| −56 | −4 | 6 | 3.48 | |||
| Insular cortex | L | −38 | −4 | 10 | 3.08 | |
| Gender differences in complex > basic emotional prosody in ASD | ||||||
| Cluster 1 | 2107 | |||||
| Planum temporale | R | 58 | −18 | 6 | 3.97 | |
| Supramarginal gyrus | R | 46 | −26 | 36 | 3.42 | |
| Superior temporal sulcus | R | 64 | −30 | 4 | 3.35 | |
| Superior temporal gyrus | R | 66 | −32 | 8 | 3.33 | |
| Planum temporale | R | 38 | −34 | 14 | 3.31 | |
| 52 | −30 | 10 | 3.22 | |||
| Implicit > explicit emotional prosody in controls > ASD | ||||||
| Cluster 1 | 1430 | |||||
| Angular gyrus | L | −44 | −68 | 44 | 4.7 | |
| −46 | −68 | 40 | 4.69 | |||
| −60 | −56 | 26 | 4.56 | |||
| Lateral occipital cortex | L | −48 | −68 | 44 | 4.48 | |
| −56 | −62 | 34 | 3.94 | |||
| −58 | −64 | 24 | 3.81 | |||
| Cluster 2 | 1218 | |||||
| Frontal pole | L | −16 | 58 | 4 | 4.07 | |
| −24 | 48 | −10 | 3.57 | |||
| −26 | 48 | −4 | 3.45 | |||
| −22 | 68 | −8 | 3.07 | |||
| Anterior cingulate cortex | L/R | −6 | 46 | 22 | 3.58 | |
| L/R | 6 | 42 | 20 | 3.33 | ||
| Cluster 3 | 1038 | |||||
| Superior frontal gyrus | L | −24 | 36 | 52 | 4.17 | |
| −20 | 28 | 30 | 4.08 | |||
| −20 | 30 | 26 | 4 | |||
| −20 | 28 | 22 | 3.9 | |||
| −18 | 36 | 54 | 3.76 | |||
| −14 | 34 | 56 | 3.51 | |||
All reported clusters are family wise error cluster corrected for multiple comparisons (FWE) at a statistical threshold of P < 0.05 and a z-value of 2.3.