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. 2016 Oct 21;8(2):1450–1453. doi: 10.1039/c6sc03702j

Fig. 1. Schematic of chemical optogenetic approach for modulating inflammatory state of macrophages. UV light irradiation of photocaged histone deacetylase (HDAC) inhibitor 1 releases SAHA, which inhibits HDAC activity and affects macrophage function by reducing inflammation through changes in gene expression.

Fig. 1