. 2017 Mar 8;6(2):168–177. doi: 10.1002/open.201600156

Table 2.

Study of Thp removal from Fmoc‐Cys(Thp)‐OH and Fmoc‐Ser(Thp)‐OH.31

Entry	Compound	Cocktail composition	Reaction time [h]	Deprotected amino acid [%]
1	Fmoc‐Cys(Thp)‐OH	100 mm MES^[a] (pH 4.8)	48	0
2	Fmoc‐Ser(Thp)‐OH	100 mm MES^[a] (pH 4.8)	40	50

3	Fmoc‐Cys(Thp)‐OH	100 mm MES, 137 mm NaCl, 2.7 mm KCl (pH 4.8)	48	0
4	Fmoc‐Ser(Thp)‐OH	100 mm MES, 137 mm NaCl, 2.7 mm KCl (pH 4.8)	20	25

5	Fmoc‐Cys(Thp)‐OH	0.1 m MES, 1.5 % TIS (pH 4.8)	48	0

6	Fmoc‐Cys(Thp)‐OH	PBS: 10 mm PO₄ ³⁻, 2.7 mm KCl, 137 mm NaCl (pH 7.4)	120	0
7	Fmoc‐Ser(Thp)‐OH	PBS: 10 mm PO₄ ³⁻, 2.7 mm KCl, 137 mm NaCl (pH 7.4)	120	0

[a] 2‐(N‐Morpholino)ethanesulfonic acid.