Table 1.
DNA motifs associated with either methylation-resistant or methylation-sensitive CpG islands.
| HPV types | E2/E4 region | MRM (MOTIFS/KIB) | MRM (MOTIFS/KIB) | MRM/MSM rate |
|---|---|---|---|---|
| All | 93 | 53.7 | 20.3 | 2.65 |
| Cutaneous | 35 | 59.9 | 16.4 | 3.65 |
| Cutaneous/mucosal | 15 | 48.4 | 20.8 | 2.33 |
| Mucosal | 43 | 50.4 | 23.2 | 2.17 |
| Cutaneous | ||||
| Warts | 10 | 51.3 | 12.3 | 4.19 |
| Epidermoplasia | 25 | 63.4 | 18.1 | 3.51 |
| Mucosal | ||||
| LR-HPV | 22 | 48.0 | 25.8 | 1.86 |
| HR-HPV | 21 | 52.9 | 20.5 | 2.58 |
Abbreviations: HPV, human papillomavirus; HR, high risk; LR, low risk; MRM, methylation-resistant CpG islands; MSM, methylation-sensitive CpG islands.