Table 3. Linear regression of model data DIAGNOSIS + AGE + SEX + ICV, assessing the importance of the diagnostic group on structural data.
MNI Coordinates | Size | ||||||
---|---|---|---|---|---|---|---|
Measurement/Structure | x | y | z | mm3 | Zmax | Zav | |
Fractional Anisotropy | |||||||
Left External Capsule | -29 | -3 | 11 | 1229 | 4.050 | 3.057 | |
Left Optic Radiation | -33 | -48 | -6 | 1120 | 3.552 | 2.865 | |
Right Optic Radiation | 20 | -59 | 3 | 1369 | 3.838 | 2.864 | |
Right Pons | 6 | -21 | -30 | 391 | 3.845 | 3.000 | |
Right Superior Temporal Gyrus | 35 | -59 | 29 | 753 | -3.654 | -2.906 | |
Left Middle Temporal Gyrus | -42 | -58 | 6 | 553 | -3.996 | -2.986 | |
Right Middle Temporal Gyrus | 44 | -53 | 6 | 651 | -3.816 | -3.074 | |
Right Postcentral Gyrus | 42 | -31 | 37 | 1093 | -3.889 | -2.927 | |
Cingulate Gyrus | 9 | 2 | 34 | 1264 | -3.021 | -2.668 | |
14 | -36 | 35 | 429 | -3.021 | -2.668 | ||
Corpus Callosum | 4 | -39 | 24 | 384 | -2.957 | -2.648 | |
-22 | -81 | 19 | 1890 | -4.785 | -2.981 | ||
Sub-Gyral WM | 25 | -21 | 54 | 514 | -3.145 | -2.705 | |
20 | -55 | 51 | 556 | -3.819 | -2.967 | ||
34 | -14 | 29 | 1263 | -4.030 | -2.926 | ||
-29 | -21 | 30 | 504 | -3.265 | -2.793 | ||
34 | 27 | 29 | 578 | -3.722 | -2.954 | ||
Left Temporal Stem | -23 | -54 | 23 | 1381 | -3.879 | -2.992 | |
Right Temporal Stem | 24 | -66 | 20 | 1739 | -3.616 | -2.843 | |
Right Midbrain | 11 | -24 | -4 | 1929 | -3.974 | -2.781 | |
Radial Diffusivity | |||||||
Left Suptraventricular WM | -21 | 33 | 37 | 940 | -3.504 | -2.769 | |
Left Postcentral Gyrus | -40 | -32 | 40 | 763 | 3.731 | 2.864 | |
Right Postcentral Gyrus | 43 | -32 | 34 | 379 | 3.619 | 2.860 | |
Left Middle Temporal Gyrus | -44 | -59 | 2 | 651 | 4.376 | 3.168 | |
Cingulate Gyrus | 9 | -6 | 39 | 543 | 3.604 | 2.861 | |
Sub-Gyral WM | -34 | -66 | 34 | 480 | 3.264 | 2.751 | |
-20 | -85 | 28 | 551 | 3.879 | 2.920 | ||
21 | -92 | 14 | 562 | 4.211 | 2.958 | ||
18 | -86 | 26 | 1512 | 3.959 | 2.893 | ||
Right Internal Capsule | 6 | -8 | 12 | 534 | 3.028 | 2.690 | |
Right Midbrain | 4 | -29 | -6 | 620 | 3.245 | 2.792 | |
Mean Diffusivity | |||||||
Left Middle Temporal Gyrus WM | -45 | -59 | 1 | 475 | 4.154 | 3.069 | |
Corpus Callosum | -18 | -23 | 29 | 3006 | -3.260 | -2.673 | |
33 | -57 | 15 | 509 | -3.286 | -2.785 | ||
-31 | -58 | 14 | 663 | -3.366 | -2.759 | ||
-16 | -71 | 5 | 412 | -3.853 | -2.931 | ||
Sub-Gyral WM | 17 | -88 | 27 | 1156 | 3.849 | 2.867 | |
-18 | -86 | 30 | 464 | 3.364 | 2.777 | ||
21 | -93 | 15 | 575 | 4.208 | 2.981 | ||
Right Internal Capsule | 5 | -8 | 12 | 469 | 3.026 | 2.692 | |
Right Midbrain | 3 | -29 | -6 | 533 | 3.242 | 2.782 | |
Axial Diffusivity | |||||||
Right Cuneus | 18 | -89 | 29 | 823 | 3.424 | 2.786 | |
Right Middle Occipital Gyrus | 21 | -94 | 16 | 612 | 4.085 | 2.946 | |
Right Pre-central WM | 34 | -16 | 31 | 2417 | -3.704 | -2.961 | |
Left Occipital Lobe WM | -20 | -43 | 26 | 6031 | -3.707 | -2.851 | |
Right Occipital Lobe WM | 31 | 53 | 20 | 4041 | -3.882 | -2.912 | |
Right Brainstem | 16 | -22 | -2 | 1039 | -4.168 | -2.893 | |
Left Brainstem | -16 | -23 | -9 | 361 | -3.421 | -2.785 |
Regions with significant differences in DTI measures FD, RD, MD, and AD are shown, with their center position, size, peak, and mean z-score. The sign of the z-scores is given relative to controls. Positive (negative) z-scores correspond to a higher (lower) value of a specific variable in the ADHD group.