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. 2017 Apr 13;12(4):e0175433. doi: 10.1371/journal.pone.0175433

Table 3. Linear regression of model data DIAGNOSIS + AGE + SEX + ICV, assessing the importance of the diagnostic group on structural data.

MNI Coordinates Size
Measurement/Structure x y z mm3 Zmax Zav
Fractional Anisotropy
Left External Capsule -29 -3 11 1229 4.050 3.057
Left Optic Radiation -33 -48 -6 1120 3.552 2.865
Right Optic Radiation 20 -59 3 1369 3.838 2.864
Right Pons 6 -21 -30 391 3.845 3.000
Right Superior Temporal Gyrus 35 -59 29 753 -3.654 -2.906
Left Middle Temporal Gyrus -42 -58 6 553 -3.996 -2.986
Right Middle Temporal Gyrus 44 -53 6 651 -3.816 -3.074
Right Postcentral Gyrus 42 -31 37 1093 -3.889 -2.927
Cingulate Gyrus 9 2 34 1264 -3.021 -2.668
14 -36 35 429 -3.021 -2.668
Corpus Callosum 4 -39 24 384 -2.957 -2.648
-22 -81 19 1890 -4.785 -2.981
Sub-Gyral WM 25 -21 54 514 -3.145 -2.705
20 -55 51 556 -3.819 -2.967
34 -14 29 1263 -4.030 -2.926
-29 -21 30 504 -3.265 -2.793
34 27 29 578 -3.722 -2.954
Left Temporal Stem -23 -54 23 1381 -3.879 -2.992
Right Temporal Stem 24 -66 20 1739 -3.616 -2.843
Right Midbrain 11 -24 -4 1929 -3.974 -2.781
Radial Diffusivity
Left Suptraventricular WM -21 33 37 940 -3.504 -2.769
Left Postcentral Gyrus -40 -32 40 763 3.731 2.864
Right Postcentral Gyrus 43 -32 34 379 3.619 2.860
Left Middle Temporal Gyrus -44 -59 2 651 4.376 3.168
Cingulate Gyrus 9 -6 39 543 3.604 2.861
Sub-Gyral WM -34 -66 34 480 3.264 2.751
-20 -85 28 551 3.879 2.920
21 -92 14 562 4.211 2.958
18 -86 26 1512 3.959 2.893
Right Internal Capsule 6 -8 12 534 3.028 2.690
Right Midbrain 4 -29 -6 620 3.245 2.792
Mean Diffusivity
Left Middle Temporal Gyrus WM -45 -59 1 475 4.154 3.069
Corpus Callosum -18 -23 29 3006 -3.260 -2.673
33 -57 15 509 -3.286 -2.785
-31 -58 14 663 -3.366 -2.759
-16 -71 5 412 -3.853 -2.931
Sub-Gyral WM 17 -88 27 1156 3.849 2.867
-18 -86 30 464 3.364 2.777
21 -93 15 575 4.208 2.981
Right Internal Capsule 5 -8 12 469 3.026 2.692
Right Midbrain 3 -29 -6 533 3.242 2.782
Axial Diffusivity
Right Cuneus 18 -89 29 823 3.424 2.786
Right Middle Occipital Gyrus 21 -94 16 612 4.085 2.946
Right Pre-central WM 34 -16 31 2417 -3.704 -2.961
Left Occipital Lobe WM -20 -43 26 6031 -3.707 -2.851
Right Occipital Lobe WM 31 53 20 4041 -3.882 -2.912
Right Brainstem 16 -22 -2 1039 -4.168 -2.893
Left Brainstem -16 -23 -9 361 -3.421 -2.785

Regions with significant differences in DTI measures FD, RD, MD, and AD are shown, with their center position, size, peak, and mean z-score. The sign of the z-scores is given relative to controls. Positive (negative) z-scores correspond to a higher (lower) value of a specific variable in the ADHD group.