Table 2. DaT-SPECT voxel-wise analysis.
| Contrast | Structure | MNI (x, y, z) |
T value |
p value FDR corrected |
Cluster size (mm3) |
|---|---|---|---|---|---|
| NMC>PD | Right striatum | 20 6 2 | 5.35 | <0.001 | 3.05 |
| Left striatum | -20 6 2 | 6.00 | <0.001 | 2.61 | |
| NMNC>PD | Right striatum | 20 6 2 | 4.96 | <0.001 | 2.88 |
| Left striatum | -20 6 2 | 5.58 | <0.001 | 2.51 | |
| NMNC>MN | Right striatum | 26 -4 -0 | 2.84 | <0.001 | 0.31 |
PD = patients with Parkinson's disease (n = 18); NMC = non-manifesting LRRK2 mutations carriers (n = 31); NMNC = non-manifesting non-carriers of LRRK2 mutations (n = 31)