Table 1. Prevalence of macrolide resistance-associated 23S rRNA gene mutations in Mycoplasma genitalium positive samples in four cities in Russia and one city in Estonia.
| Mutationa | Frequency, % (No of samples containing mutation(s)/No of successfully sequenced samples) | ||||||
|---|---|---|---|---|---|---|---|
| Russia | Estonia | Total | |||||
| Moscow | St Petersburg | Smolensk | Tula | Total | Tartu | ||
| A2059G | 3.6 (14/391) | 6.8 (4/59) | 1.6 (2/127) | 2.8 (20/719) | 6.4 (7/110) | 3.3 (27/829) | |
| A2058G | 1.3 (5/391) | 3.1 (4/127) | 0.7 (1/142) | 1.4 (10/719) | 2.7 (3/110) | 1.6 (13/829) | |
| A2058C | 0.3 (1/391) | 0.1 (1/719) | 0.1 (1/829) | ||||
| A2058T | 0.3 (1/391) | 0.1 (1/719) | 0.1 (1/829) | ||||
| A2062G | 0.3 (1/391) | 0.1 (1/719) | 0.1 (1/829) | ||||
| C2055G | 0.9 (1/110) | 0.1 (1/829) | |||||
| Total | 5.6 (22/391) | 6.8 (4/59) | 4.7 (6/127) | 0.7 (1/142) | 4.6 (33/719) | 10 (11/110) | 5.3 (44/829) |
| In 2013: 6.7 (2/30); in 2014: 7.7 (2/26); in 2015: 0 (0/3) | In 2009–2012: 5.3 (1/19); in 2013: 4.2 (1/24); in 2014: 10.7 (3/28); in 2015: 1.8 (1/56) | In 2014: 7.1 (6/84); in 2016: 19.2 (5/26) | |||||
aThe nucleotide positions in the 23S rRNA gene are given according to Escherichia coli numbering.