Fig 4. The enamel organ epithelium of the incisors of Slc13a5-/- mice was disorganized and dysplastic in all stages of amelogenesis.
Representative images of decalcified, paraffin-embedded sections of lower incisors (A-I) from 32- week-old Slc13a5+/+ (A, D, G), Slc13a5+/- (B, E, H) and Slc13a5-/- (C, F, I) mice. Images A to C were from the secretory stages of amelogenesis of the incisors near the apex of the tooth, D to F from the maturation stages of amelogenesis at the level of the first molar, and G to I from the post-maturation stages of amelogenesis near the site of eruption. Hematoxylin and Eosin. em = enamel matrix; es = enamel space.