Table 2. Patient clinical and left ventricular systolic echocardiographic parameters.
| Before anthracycline chemotherapy | After anthracycline chemotherapy | |
|---|---|---|
| Haemoglobin (g/L) | 131 ± 12 | 117 ± 12 * |
| eGFR (mL/min/1.73m2) | 84 ± 9 | 85 ± 11 |
| Creatinine (umol/L) | 62 ± 10 | 61 ± 15 |
| BSA (m2) | 1.8 ± 0.2 | 1.8 ± 0.2 |
| Heart rate (bpm) | 71 ± 11 | 78 ± 11 * |
| MAP (mmHg) | 90 ± 10 | 90 ±10 |
| LV mass (g/m2) | 75 ± 17 | 78 ± 16 |
| Cardiac output (L/min) | 5.0 ±1.2 | 5.2 ± 1.2 |
| LVEDV (mL/m2) | 53 ± 9 | 54 ± 11 |
| LVESV (mL/m2) | 21 ± 4 | 22 ± 5 * |
| Stroke volume (mL/m2) | 30 ± 6 | 30 ± 6 |
| LVEF (%) | 60 ± 3 | 59 ± 3 * |
| S' (cm/s) | 8.1 ± 1.4 | 8.1 ± 1.6 |
| Biplane GLS (%) | -20.3 ± 1.7 | -19.3 ± 1.8 * |
| Triplane GLS (%) | -20.0 ± 1.6 | -19.1 ± 1.8 * |
| Ssr (s-1) | -1.4 ± 0.2 | -1.4 ± 0.2 |
| Radial strain (%) | 41.5 ± 10.2 | 41.3 ± 10.6 |
| Circumferential strain (%) | -21.8 ± 3.4 | -20.7 ± 3.1 * |
eGFR = estimated globular filtration rate; LVEDV = left ventricular end diastolic volume; LVESV = left ventricular end systolic volume; LVEF = left ventricular ejection fraction; GLS = global longitudinal strain; Ssr = systolic strain rate;
* p<0.05 compared with baseline value