Skip to main content
. 2017 Apr 13;12(4):e0175544. doi: 10.1371/journal.pone.0175544

Table 2. Patient clinical and left ventricular systolic echocardiographic parameters.

Before anthracycline chemotherapy After anthracycline chemotherapy
Haemoglobin (g/L) 131 ± 12 117 ± 12 *
eGFR (mL/min/1.73m2) 84 ± 9 85 ± 11
Creatinine (umol/L) 62 ± 10 61 ± 15
BSA (m2) 1.8 ± 0.2 1.8 ± 0.2
Heart rate (bpm) 71 ± 11 78 ± 11 *
MAP (mmHg) 90 ± 10 90 ±10
LV mass (g/m2) 75 ± 17 78 ± 16
Cardiac output (L/min) 5.0 ±1.2 5.2 ± 1.2
LVEDV (mL/m2) 53 ± 9 54 ± 11
LVESV (mL/m2) 21 ± 4 22 ± 5 *
Stroke volume (mL/m2) 30 ± 6 30 ± 6
LVEF (%) 60 ± 3 59 ± 3 *
S' (cm/s) 8.1 ± 1.4 8.1 ± 1.6
Biplane GLS (%) -20.3 ± 1.7 -19.3 ± 1.8 *
Triplane GLS (%) -20.0 ± 1.6 -19.1 ± 1.8 *
Ssr (s-1) -1.4 ± 0.2 -1.4 ± 0.2
Radial strain (%) 41.5 ± 10.2 41.3 ± 10.6
Circumferential strain (%) -21.8 ± 3.4 -20.7 ± 3.1 *

eGFR = estimated globular filtration rate; LVEDV = left ventricular end diastolic volume; LVESV = left ventricular end systolic volume; LVEF = left ventricular ejection fraction; GLS = global longitudinal strain; Ssr = systolic strain rate;

* p<0.05 compared with baseline value