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. 2017 Apr 13;12(4):e0175544. doi: 10.1371/journal.pone.0175544

Table 4. Left ventricular diastolic parameters.

Before anthracycline chemotherapy After anthracycline chemotherapy
Mitral inflow E Velocity (m/s) 0.68 ± 0.14 0.64 ± 0.13 *
A Velocity (m/s) 0.63 ± 0.14 0.64 ± 0.16
E/A ratio 1.13 ± 0.32 1.04 ± 0.29 *
Deceleration time (ms) 212 ± 40 212 ± 44
Atrial fraction (%) 36.0 ± 7.0 39.6 ± 8.5 *
Pulmonary vein flow Systolic velocity (m/s) 0.50 ± 0.14 0.49 ± 0.16
Diastolic velocity (m/s) 0.41 ± 0.12 0.38 ± 0.12 *
Atrial reversal velocity (cm/s) 0.27 ± 0.07 0.27 ± 0.09
Tissue Doppler imaging E’ average velocity (cm/s) 9.1 ± 2.4 8.4 ± 2.6 *
E/E’ average ratio 7.6 ± 2.3 7.7 ± 2.5
A’ average velocity (cm/s) 9.0 ± 2.4 9.1 ± 2.2
LV diastolic grade Normal (%) 53 42 *
Impaired (%) 46 57 *
Pseudonormal (%) 1 1
Strain rate Esr (s-1) 1.54 ± 0.23 1.48 ± 0.23 *
E/Esr (s-1) 0.44 ± 0.10 0.44 ± 0.10
Asr (s-1) 0.98 ± 0.24 1.04 ± 0.22 *

* p<0.05 compared with baseline value

Esr = early diastolic strain rate; Asr = late diastolic strain rate