Table 4. Left ventricular diastolic parameters.
Before anthracycline chemotherapy | After anthracycline chemotherapy | ||
---|---|---|---|
Mitral inflow | E Velocity (m/s) | 0.68 ± 0.14 | 0.64 ± 0.13 * |
A Velocity (m/s) | 0.63 ± 0.14 | 0.64 ± 0.16 | |
E/A ratio | 1.13 ± 0.32 | 1.04 ± 0.29 * | |
Deceleration time (ms) | 212 ± 40 | 212 ± 44 | |
Atrial fraction (%) | 36.0 ± 7.0 | 39.6 ± 8.5 * | |
Pulmonary vein flow | Systolic velocity (m/s) | 0.50 ± 0.14 | 0.49 ± 0.16 |
Diastolic velocity (m/s) | 0.41 ± 0.12 | 0.38 ± 0.12 * | |
Atrial reversal velocity (cm/s) | 0.27 ± 0.07 | 0.27 ± 0.09 | |
Tissue Doppler imaging | E’ average velocity (cm/s) | 9.1 ± 2.4 | 8.4 ± 2.6 * |
E/E’ average ratio | 7.6 ± 2.3 | 7.7 ± 2.5 | |
A’ average velocity (cm/s) | 9.0 ± 2.4 | 9.1 ± 2.2 | |
LV diastolic grade | Normal (%) | 53 | 42 * |
Impaired (%) | 46 | 57 * | |
Pseudonormal (%) | 1 | 1 | |
Strain rate | Esr (s-1) | 1.54 ± 0.23 | 1.48 ± 0.23 * |
E/Esr (s-1) | 0.44 ± 0.10 | 0.44 ± 0.10 | |
Asr (s-1) | 0.98 ± 0.24 | 1.04 ± 0.22 * |
* p<0.05 compared with baseline value
Esr = early diastolic strain rate; Asr = late diastolic strain rate