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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Nov 5;101:134–144. doi: 10.1016/j.yjmcc.2016.10.016

Figure 2.

Figure 2

a) The eight lowest energy solution NMR structures of cChimera (cTnI switch region shown in red). b) The x-ray structure cNTnC-cTnI derived from the cardiac troponin complex (1J1E.pdb, grey) was aligned by secondary structural elements (residues 3–85) to cChimera (cNTnC region: blue, cyan, green, and yellow spectrum, cTnI inhibitory region linker: orange, cTnI switch region: red). c) Residue Val146 of cTnI (red) forms contacts with Pro52, Glu56 and Met60 (green) of cNTnC, shown in sticks.