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. 2017 Apr 15;28(8):1132–1146. doi: 10.1091/mbc.E16-07-0485

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© 2017 Upadhyay et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 5: — Relocalization of NLS and mutation in endonuclease in CENPB in S. pombe and H. sapiens. (A) Comparison of domains present in Tc1/mariner transposases, Tc5/Tigger transposases, human CENPB, and fission yeast CENPB. (B) Sequence alignment of Tc1/mariner, Tc5/Tigger, and CENPB proteins from different species were studied for the localization of NLS. Data collected from the CDD. The residues represented by red and spanned by the black line represent the HTH-Tn-Tc5 DNA–binding domain (DBD), and green indicates predicted NLS sequences (NLS overlaps with DBD).