Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 15;28(8):1147–1159. doi: 10.1091/mbc.E16-09-0632

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Borze˛cka-Solarz et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

“ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

PMC Copyright notice

FIGURE 3: — Wild-type and constitutively active Lyn inhibit and kinase-dead Lyn up-regulates LPS-induced production of TNF-α and CCL5/RANTES in RAW264 cell. Cells transfected with indicated constructs of Lyn-GFP or GFP alone were stimulated with 100 ng/ml LPS for 4 or 6 h for TNF-α and CCL5/RANTES measurements, respectively. Concentration of TNF-α (A) and CCL5/RANTES (C) in culture supernatants was measured with ELISA and expression of respective genes (B, D) analyzed using real-time quantitative PCR. Results are mean ± SD from one experiment run in triplicate and are representative of two or three independent experiments. *Significantly different from LPS-stimulated cells transfected with GFP alone at p ≤ 0.05.